Comprehensive Screening And Tests For Treating Infertility

Are you trying to get pregnant for a long time but so far, no luck? If a couple is unsuccessful at achieving pregnancy after trying for more than a year, it is recommended to undergo a thorough fertility screening and take the right assessment tests. A comprehensive fertility screening and assessment for the couple helps a doctor guide better with any treatments.  

Female Diagnosis 

Ultrasound – Sonohysterogram (SHG): It is an imaging procedure to study the uterus's shape and structure. Abnormal uterus shape, fibroid growth in the uterus or any other issues also cause fertility issues in a woman.

Endocrine Assessment: It is a hormone test for assessment of the entire endocrine system to analyse if there is any dysfunction causing infertility.

Ovarian Reserve Testing: The ovarian reserve measures the number of eggs in a female. It is a simple blood test that measures the levels of AMH (Anti-Mullerian Hormone) and AFC (Antral Follicle Count) that depicts the current ovarian reserve.

Tubal Assessment – Hysterosalpingogram: The HSG is a fluoroscope examination of the uterus and fallopian tubes. It helps identify the uterus morphology and investigates infertility or the cause of recurrent abortions.

Hysteroscopy: The procedure involves the insertion of a thin, flexible tube called a hysteroscope through the vagina. It examines the cervix and uterus to check for any abnormality that might be the reason for infertility.

HyCoSy/HyFoSy: HyCoSy (hysterosalpingo-contrast sonography) and HyFoSy (hysterosalpingo-foam sonography) is a diagnostic ultrasound procedure used for examining the uterine lining. The procedure also examines the health of the fallopian tubes.

Immunological Investigation: The test involves checking for immunological infertility, which is the presence of pathological antisperm immunity that prevents fertilisation of the egg and its embryo implantation.

Semen Analysis: The procedure is done to check for male fertility screening. It is also known as the sperm count test, which tests the health and viability of the sperm. It evaluates the sperm count, motility, morphology etc.

Post-ejaculation urinalysis: The test checks for sperm in the urine after ejaculation. The test is done when semen volume is low because of retrograde ejaculation, which is the backward flow of semen in the bladder rather than its flow out via the urethra. Retrograde ejaculation is one of the prominent causes of male infertility.

Testicular Biopsy: The procedure involves testing a small tissue sample from the testicle to diagnose the cause of male infertility. The tissue portion is analysed in a lab to detect the presence or absence of sperm.

Genomic 

Genetic Disorders: There are many genetic disorders like Kleinfelter syndrome, cystic fibrosis gene mutation, Noonan syndrome etc., in male and Fragile-X Syndrome, Kallmann Syndrome etc., in female that causes infertility.

Genetic tests: There are underlying genetic issues that cause infertility in males and females. Advanced genetic testing helps in identifying the cause of infertility through proper assessment. 

PGT-A: It stands for preimplantation genetic testing for aneuploidy. The technique is used for screening for chromosomal abnormalities in eggs and embryos. It even helps in identifying birth defects such as Down Syndrome. 

PGT-SR: The PGT – SR (Structural rearrangement) is a genetic test that checks for chromosomal abnormality in embryos caused by specific structural rearrangement. 

PGT-M: It stands for Preimplantation genetic test – monogenic, and is a genetic test to check for chromosomal abnormality in the embryo.

Chromosomal karyotyping: The genetic test evaluates the number and structure of chromosomes in an embryo to detect abnormalities. 

Endometrial Microbiota Analysis (EMMA/Alice): The screening test or analysis checks for abnormal endometrial microbiota that might cause loss of pregnancy or implantation failure. 

Product of conception: This is the fetal or placental tissue that remains within the uterus after a miscarriage. The genetic screening of the product of conception helps in understanding if any issue leads to infertility. 

Sperm Anaploidy Screening: The diagnostic tool is a genetic test for men examining the sperm chromosome for abnormalities. It identifies the presence of defective chromosomes in the semen.

PGT – Pre genetic testing/ PGS – Pre genetic screening: The PGT/PGS are screening techniques that evaluate the chromosomal makeup of the embryo. Genetic testing screens for embryos before implantation reduces miscarriage rates and implantation failures. 

Sperm DNA Fragmentation Testing: DNA fragmentation testing measures the amount of damaged DNA in sperm. If there is a high percentage of damage, it causes difficulty in achieving pregnancy. 

You can request an appointment easily at Apollo Fertility, Banjara Hills, for a consultation by calling 1860 500 4424.

1. How to conduct fertility tests and screening?

If you are trying to get pregnant and not able to for over a year, visit Apollo Fertility Clinic for a complete assessment. The doctors will conduct a series of test for both male and female to understand root causing infertility.

2. What is the purpose of sperm DNA fragmentation testing?

The test is for checking out presence of male infertility. The test measures amount of damaged DNA in sperm. High amount of damage amounts of male infertility issues.

3. I was detected with fibroid. Can it cause infertility?

Fibroids in uterus is a prominent cause of female infertility. It is best to take a sonohysterogram (HCG) for studying any abnormal growth in the uterus. With help of infertility treatments, you can try conceiving again after the removal of the fibroid.

4. How can retrograde ejaculation cause infertility?

It is one of the causes of male infertility. The test helps in measuring semen volume. Low semen volume might be due to backward flow of semen in bladder reducing sperm flow.

5. What is the cost of the fertility test?

There are different types of fertility tests that involves checking for oocyte count, sperm count, genetic testing, analysing the endocrine system and many more. Each of the test has different cost and depends on the complexity.

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